| 10 Respiratory
diseases
and
travel
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10.1 Introduction
Respiratory infections are common both at home and
abroad and frequently affect people while travelling. Certain
situations which may be encountered when travelling, and certain
infections, place the traveller at some increased risk of a respiratory
infection.
10.2 Acute respiratory infections
Some travellers spend considerable periods in crowded
conditions or communal living which may increase the risk of acute
respiratory infections such as colds, influenza and bronchitis.
Most are self-limiting virus infections for which there is no
specific treatment. If symptoms persist or worsen, medical attention
should be sought. Practitioners should be aware that respiratory
pathogens acquired abroad may have unusual antimicrobial resistance
patterns.
10.3 Influenza and pneumococcal infections
Influenza infection occurs throughout the world mainly
in winter (it should be remembered that in the southern hemisphere
this is during the summer months of the northern hemisphere).
In the tropics, influenza activity is not seasonal. For most travellers
no specific protection against influenza is recommended and treatment
should be symptomatic. Influenza immunisation before travel should
be considered for individuals for whom annual influenza immunisation
is recommended in the UK, such as those (of any age) with certain
chronic underlying diseases and those aged 65 and over.
The risk of pneumococcal infection is increased in
certain groups and increases with age; high altitude may add to
the risk. Immunisation is advised for those at increased risk
in accordance with the recommendations in Immunisation
against Infectious Disease.
10.4 Legionnaires' disease
Legionnaires' disease is an uncommon form
of pneumonia or severe chest infection which has a significant
mortality, particularly among middle aged or elderly adults. It
may be contracted anywhere in the world. Both sporadic cases and
outbreaks of legionnaires' disease have been reported among
holiday makers who have stayed in hotels and apartment blocks,
particularly around the Mediterranean. Although the risk for any
individual is extremely small, the diagnosis should be considered
in travellers who develop a respiratory illness, particularly
pneumonia, during or on return from their travel, so that appropriate
treatment can be instituted promptly. No preventive measures against
acquiring legionnaires' disease are available to the individual.
Use of a rapid diagnostic test (e.g. detection of
antigen in urine) will enable rapid and appropriate antibiotic
treatment to be given, thus reducing the risk of severe illness
and death from this disease.
10.5 Tuberculosis
Tuberculosis (TB) is one of the major global public
health challenges. The World Health Organization estimates that
one third of the world's population is infected with TB,
and it is the major cause of death from a single infectious agent
among adults in the developing world. There has been some increase
in TB in parts of the industrialised world.
In many countries of Africa and Asia, infection with
HIV has further increased morbidity and mortality from TB: TB
is responsible for about 40 per cent of AIDS-related deaths in
Africa. Drug resistant TB is increasing in many areas of the world.
Among travellers from industrialised countries, the
families of migrants returning to visit relatives abroad are particularly
at risk. The risk for other travellers is limited as transmission
of the infection usually requires prolonged close contact.
Regions of the world can be categorised based on
the incidence of cases of tuberculosis reported to the World Health
Organization. The incidence of tuberculosis is generally high
in Africa, Asia and South America and low in industrialised countries.
Some countries within global regions may, however, have incidence
rates that differ substantially from that seen in the rest of
their region. For countries in low risk regions, with an incidence
rate of up to 40 per 100,000 population, no specific recommendation
for BCG immunisation is made for travellers. For countries defined
as high risk (incidence rate over 40 per 100,000 population),
BCG is recommended for visits longer than about a month, particularly
if living or working with the local population. (See under disease
risks for each area for the risk for particular countries).
BCG should only be offered to those not previously
immunised and who have a negative tuberculin skin test (see Immunisation
against Infectious Disease for further
details).
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